Follicular Lymphoma International Prognostic Index. Arenillas , S. Blood. Feb 28, 2025 · To date, several progn

Arenillas , S. Blood. Feb 28, 2025 · To date, several prognostic models have been developed to predict survival in FL, such as Follicular Lymphoma International Prognostic Index (FLIPI) [5], FLIPI2 [6], PRIMA-Prognostic Index (PRIMA-PI) [7], but their predictive effect on prognosis of elderly patients still needs to be further validated. The FLIPI includes five adverse prognostic factors: Age (≥60 vs <60 years), +11 2017Hematological OncologyIS3. Performance status (PS) was assessed using the Eastern Cooperative Oncology Group (ECOG) scale. Immunochemotherapy induces long-term responses in patients with follicular lymphoma. From this database, a prognostic index with five adverse factors was derived and validated. Mar 6, 2025 · Risk assessment typically relies on histological grade, tumor burden, and the Follicular Lymphoma International Prognostic Index, which incorporates factors like age, hemoglobin level, and Ann Arbor stage. 1200/JCO. g. Follicular lymphoma (FL) is the most commonly diagnosed indolent lymphoma with an incidence ranging from 2. Progression-free survival according to FLIPI (A) and FLIPI-2 (B) in 107 patients with follicular lymphoma. Retrospective analysis of prognostic factors for angioimmunoblastic T-cell lymphoma: a multicenter cooperative study in Japan. 1. AI generated definition based on: Leukemia Research, 2016 The Follicular Lymphoma International Prognostic Index, or FLIPI, is a standardized guide to help oncological diagnosticians accurately calculate survival rates based on certain factors. The study took place during 1985 and 1992 on patients diagnosed with follicular lymphoma and treated with a range of chemotherapy drugs, excluding rituximab. All the patients were diagnosed again by immunohistochemical staining. Results were very similar in the confirmation group. This cancer is a form of Non-Hodgkin Lymphoma and it originates from the uncontrolled division of specific types of B-cells (centrocytes and centroblasts). Kustakin tekijästä saa yhden riskipisteen. 9904 Early Disease Progression Predicts Poorer Survival in Patients with Follicular Lymphoma (FL) in the GALLIUM Study Early Disease Progression Predicts Poorer Survival in Patients with Follicular Lymphoma (FL) in the GALLIUM Study A A. The Follicular Lymphoma Interntional Prognostic Index (FLIPI) estimates overall survival based on clinical information. The Follicular Lymphoma International Prognostic Index (FLIPI) is the result of a large international cooperative effort in which clinical data was collected from 4167 patients with FL diagnosed between 1985 and 1992. However, clinical decisions are rarely made based on these and other indices. proposed the follicular lymphoma international prognostic index (FLIPI) as a model to predict FL survival in patients receiving chemotherapy and tested the FLIPI in FL patients diagnosed between 1985 and 1992 [5]. 2020 Jan 2;9 (12):104. There is currently no clear consensus on the standard of care for relapsed or refractory follicular lymphoma (FL) beyond third-line therapy, where both anti-CD19 CAR-T-cell therapy (CAR-T) and CD3 6） Federico M, et al. Sep 1, 2006 · The Follicular Lymphoma International Prognostic Index (FLIPI) separates high-risk from intermediate- or low-risk patients with advanced-stage follicular lymphoma treated front-line with rituximab and the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) with respect to treatment outcome Christian Buske , Eva Abstract Background: Because follicular lymphoma (FL) patients have heterogeneous outcomes, the FL international prognostic index (FLIPI) was developed to risk-stratify patients and to predict survival. The relationship of FLIPI score and lymphoma has been the subject of debate, but it is largely valued as a tool. Martínez , L. Hiddemann U Ulrich Duenzinger F Fingerle-Rowson G T T Nov 15, 2022 · We report the FL International Prognostic Index model developed specifically to predict the risk of event within 24 months (EFS24) of starting first-line immunochemotherapy (IC) (FLIPI24). Villamor , A. 8%]), advanced stage disease (84. The development of next-generation sequencing technologies has allowed the integration of somatic gene mutations into clinical scores to build genotyped-based risk models, such as the m7–Follicular Lymphoma International Prognostic Index (FLIPI). 1994. However, the toxicity of chemotherapy remains a relevant challenge. Dr Philippe Solal-Célignym, the creator of FLIPI is a professor and principal investigator at Laboratoire Central d’Hematologie at Centre Jean Bernard in France. FLIPI is designed to be used in patients with follicular lymphoma and to risk stratify patients based on prognosis. 5 The index was developed following a retrospective analysis of data collected from over 4,000 patients with FL diagnosed between 1985 and 1992. BL Jan 2, 2026 · Article PDF Available Prognostic impact of smoking and alcohol consumption in male patients with diffuse large B-cell lymphoma: a multicenter retrospective study January 2026 Blood Research 61 (1) Patients with non-Hodgkin's lymphoma can respond to rituximab despite having factors associated with a poor outcome to chemotherapy, and the follicular lymphoma international prognostic index (FLIPI) did not correlate consistently with response to ritonavir or response duration.

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